White Blood Cells (WBC / Leukocytes)
The immune system's frontline defense. White blood cells fight infections and respond to inflammation.
What are White Blood Cells?
White blood cells, also called leukocytes or WBCs, are the soldiers of your immune system. Unlike red blood cells that carry oxygen, white blood cells defend your body against infections, viruses, bacteria, and other foreign invaders.
Your bone marrow produces white blood cells, which then circulate through your blood and lymphatic system, ready to respond to threats.
A complete blood count (CBC) measures your total white blood cell count and can break it down into different types, each with specific roles.
Normal Ranges
| Marker | Normal Range |
|---|---|
| Total WBC | 4,000โ11,000 cells/ยตL |
| Neutrophils | 40โ70% of WBC |
| Lymphocytes | 20โ40% of WBC |
| Monocytes | 2โ8% of WBC |
| Eosinophils | 1โ4% of WBC |
| Basophils | 0โ1% of WBC |
Types of White Blood Cells
Neutrophils
The first responders. They attack bacteria and fungi. Elevated neutrophils often indicate bacterial infection.
Lymphocytes
Include T cells, B cells, and natural killer cells. They handle viruses, coordinate immune responses, and create antibodies.
Monocytes
The cleanup crew. They engulf dead cells and pathogens, and become macrophages in tissues.
Eosinophils
Rise during allergic reactions and parasitic infections.
Basophils
Involved in allergic and inflammatory responses. The rarest type.
Why It Matters
Infection Detection
Elevated WBC often indicates your body is fighting an infection. The pattern of elevation (which cell types are high) helps identify the type of infection.
Immune System Health
Low WBC counts may indicate immune suppression from medications, viral infections, or bone marrow problems.
Chronic Disease Monitoring
Conditions like autoimmune diseases, leukemia, and other blood disorders affect white blood cell counts and distribution.
High vs. Low WBC
High WBC (Leukocytosis)
- Bacterial infections
- Inflammation
- Stress response
- Certain medications (steroids)
- Rarely: leukemia
Low WBC (Leukopenia)
- Viral infections
- Bone marrow suppression
- Autoimmune conditions
- Certain medications
How Often to Test
- Routine checkups: Included in standard CBC
- During illness: To monitor infection response
- Taking immunosuppressants: Regularly as directed
Related Biomarkers
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