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USE CASE

Kidney Health Tracking: eGFR and Creatinine Over Time

How Healthbase helps you track kidney function markers like eGFR and creatinine to catch changes early and monitor long-term kidney health.

Kidney function declines naturally with age, but that decline can accelerate due to medications, conditions like diabetes or hypertension, or other factors. Since kidney disease often has no symptoms until it's advanced, tracking kidney function over time is the only way to catch problems early.

Healthbase helps you monitor the biomarkers that matter for kidney health.

Why Kidney Tracking Matters

Your kidneys filter waste from your blood, balance fluids, and regulate blood pressure. When they're functioning well, you don't notice them. When function declines significantly, the consequences are serious.

The challenge is that kidney function can deteriorate substantially before you feel anything wrong. By the time symptoms appear, significant damage may have occurred.

Regular monitoring catches decline early, when lifestyle changes or medical intervention can slow or stop progression.

Key Kidney Biomarkers

eGFR (Estimated Glomerular Filtration Rate)

eGFR is the primary measure of kidney function. It estimates how well your kidneys are filtering blood.

eGFR LevelWhat It Means
90+Normal or high
60-89Mildly decreased
45-59Mild to moderate decrease
30-44Moderate to severe decrease
15-29Severely decreased
<15Kidney failure

Normal kidney function declines about 1 mL/min/year after age 40. Faster decline warrants investigation.

Creatinine

Creatinine is a waste product from muscle metabolism. Your kidneys filter it out; when kidney function decreases, creatinine levels rise.

Creatinine is used to calculate eGFR. Tracking it directly can also be informative, especially for understanding what's driving eGFR changes.

BUN (Blood Urea Nitrogen)

Another waste product filtered by kidneys. Often measured alongside creatinine. The BUN/creatinine ratio can provide additional diagnostic information.

Urine Albumin (or Urine Protein)

Protein in urine indicates kidney damage, sometimes before eGFR declines. If you're at risk for kidney disease, urine tests are important to track alongside blood tests.

Who Should Track Kidney Function

Everyone Over 40

Kidney function naturally declines with age. Annual monitoring helps you understand your personal trajectory.

People With Diabetes

Diabetes is the leading cause of kidney disease. If you have diabetes, kidney monitoring is essential.

People With Hypertension

High blood pressure damages kidneys over time. Regular monitoring catches this early.

People on Certain Medications

Some medications — including common ones like NSAIDs, certain blood pressure medications, and some antibiotics — can affect kidney function. If you take these regularly, monitoring is prudent.

People With a Family History

If kidney disease runs in your family, you're at higher risk and should monitor more closely.

What Healthbase Does

Track All Kidney Markers

Upload lab results from any provider. Healthbase extracts and organizes all kidney-relevant markers: eGFR, creatinine, BUN, and any urine tests you've had.

See Trends Over Time

One eGFR result tells you your kidney function right now. Years of results show whether function is stable, declining normally for age, or declining faster than expected.

This trend is what matters. A slow, steady decline might be normal aging. An accelerating decline needs investigation.

Correlate With Other Factors

Kidney function relates to blood pressure, blood sugar, medications, and other factors. Seeing everything together helps identify what might be affecting your kidneys.

Prepare for Nephrology Appointments

If you see a nephrologist (kidney specialist), generate a summary of your kidney function over time. They see where you are now and how you got there.

Tracking in Practice

Annual Monitoring

For most people, annual kidney function testing is appropriate. Request eGFR/creatinine as part of your regular bloodwork.

More Frequent for At-Risk

If you have diabetes, hypertension, or known kidney issues, more frequent monitoring (every 3-6 months) may be appropriate.

After Medication Changes

If you start a medication that might affect kidneys, check function before starting and after a few weeks.

Watch the Trend

Don't fixate on individual numbers. Watch how values change over time. A temporary blip might mean nothing. A consistent trend matters.

Early Action Matters

If kidney function is declining faster than expected, early action can slow or stop progression. Lifestyle changes (blood pressure control, blood sugar management, dietary modifications) and medication adjustments can make a significant difference — but only if the problem is caught early.

By the time someone feels kidney disease symptoms, options are more limited. Tracking is how you stay ahead of the problem.

Your kidneys work silently. Tracking kidney function gives you visibility into their health before problems become serious.

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